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Key Features Effective Anti-Allergy Relief

If you have a stuffy nose, coughing, or itchy or watery eyes because of allergies or hay fever, Phenergan Elixir can help. No matter what time of year it is, Phenergan can help right away.

Nausea and Motion Sickness Aid

This product is great for people who need reliable relief when travelling or having stomach problems because it is made to help with nausea, vomiting, and motion sickness.

Escitalopram, tablets are used to relieve the symptoms of depression, anxiety, and obsessive-compulsive disorder (OCD) in adults. This medication works by increasing the levels of serotonin, a natural substance in the brain that helps maintain mental balance.

Please remember, that steroid use can be harmful, this is sold for research purposes only. If you intend to take these products, please do so under your GP’s advice. Steroid abuse is no joke and can potentially lead to serious health complications. Blood work before, during, and after use is strongly advised.

  • 2.5mg/0.5mL
  • 5mg/0.5mL
  • 7.5mg/0.5mL
  • 10mg/0.5mL
  • 12.5mg/0.5mL
  • 15mg/0.5mL
  • CHOOSE YOUR DOSE AND FILL IT IN WHEN CHECKING OUT,AS THERE IS A SPACE FOR THAT
Mounjaro weight loss

Weight Loss Treatments

Use this flavoured laxative to return your bowel movements to normal health.

Laxido orange

Laxido paediatric

Laxido Sachets

Laxido Sachets orange powder is an orange-flavored laxative for use in the treatment of constipation and is especially effective if you have been constipated for a long time. It may also be used to clear fecal impaction, which may occur if you have been constipated for a long time. The active ingredient is Macrogol which is an osmotic laxative, this makes the feces softer and easier to pass, giving you gentle relief. The electrolytes help to maintain the body’s normal sodium, potassium, and water levels whilst treating constipation.

How do I take Laxido Sachets Orange Powder?

Empty the Laxido sachet of powder into a glass of water, stir, and drink.

For constipation, the usual dose is one sachet taken one to three times daily. A course of treatment should last no longer than 2 weeks unless you have other conditions or are taking medication that causes constipation.

For fecal impaction, the usual dose is eight sachets daily. All eight sachets must be taken within six hours. If you have a heart condition, do not take more than two sachets (in 250ml of water) in any one hour. A course of treatment should last no longer than three days.

Laxido Sachets contains the active ingredient Macrogol 3350, which is a laxative used for the treatment of constipation, especially if you have been constipated for a long time. It is also used to treat a build-up of hard feces in your bowel which may be a result of long-term constipation (this is known as fecal impaction).

Macrogol 3350 makes your feces softer and easier to pass, giving you relief from constipation. The electrolytes help to maintain your body’s normal levels of sodium, potassium, and water while you are being treated for constipation.

Escitalopram, tablets are used to relieve the symptoms of depression, anxiety, and obsessive-compulsive disorder (OCD) in adults. This medication works by increasing the levels of serotonin, a natural substance in the brain that helps maintain mental balance.

Escitalopram

Escitalopram is a widely prescribed antidepressant medication that belongs to a class of drugs known as Selective Serotonin Reuptake Inhibitors (SSRIs). It is primarily used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Below is a comprehensive overview of the drug:

🔬 Chemical and Pharmacological Details
  • Generic Name: Escitalopram

  • Brand Names: Lexapro (USA), Cipralex (EU), among others

  • Chemical Structure: (S)-(+)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile

  • Molecular Formula: C20H21FN2O

  • Drug Class: SSRI (Selective Serotonin Reuptake Inhibitor)

Escitalopram is the S-enantiomer of citalopram, meaning it is the more pharmacologically active part of the citalopram molecule.

🧠 Mechanism of Action

Escitalopram works by increasing serotonin levels in the brain. It does this by inhibiting the reuptake (reabsorption) of serotonin (5-HT) into the presynaptic neuron, thereby increasing its availability in the synaptic cleft. This improved serotonin signaling is believed to enhance mood and reduce anxiety.

💊 Therapeutic Uses
  • Major Depressive Disorder (MDD)

  • Generalized Anxiety Disorder (GAD)

  • Obsessive-Compulsive Disorder (OCD) – off-label

  • Panic Disorder – off-label

  • Social Anxiety Disorder (SAD) – off-label

  • Post-Traumatic Stress Disorder (PTSD) – off-label

  • Premenstrual Dysphoric Disorder (PMDD) – off-label

  • ⚖️ Dosage and Administration
    • Typical Adult Dose for Depression or Anxiety:

      • Initial: 10 mg once daily

      • Maximum: 20 mg/day

    • Elderly or Hepatic Impairment:

      • Recommended: Start at 5 mg daily

    • Pediatric Use:

      • Approved for adolescents (≥12 years) in some countries

    It is usually taken orally once daily, with or without food.

    Pharmacokinetics
    • Bioavailability: ~80%

    • Time to peak plasma concentration: 4–5 hours

    • Half-life: ~27–32 hours

    • Metabolism: Primarily in the liver via CYP2C19, CYP2D6, and CYP3A4

    • Excretion: Renal (kidneys)

    ⚠️ Warnings and Precautions
    • Black Box Warning (USA): May increase the risk of suicidal thoughts and behaviors in children, adolescents, and young adults.

    • Serotonin Syndrome: Risk increases when combined with other serotonergic agents (e.g., MAOIs, triptans, tramadol).

    • QT Prolongation: Can cause abnormal heart rhythms at higher doses.

    • Discontinuation Syndrome: Abrupt stopping may lead to symptoms like dizziness, insomnia, irritability, and brain “zaps”.

    🤕 Common Side Effects
    • Nausea

    • Headache

    • Drowsiness or insomnia

    • Dry mouth

    • Increased sweating

    • Sexual dysfunction (e.g., decreased libido, delayed ejaculation)

    • Fatigue or dizziness

    • Appetite or weight changes

    🚫 Contraindications
    • Concurrent use with monoamine oxidase inhibitors (MAOIs)

    • Known hypersensitivity to escitalopram or citalopram

    • Use with pimozide (due to QT prolongation risk)

    💊 Drug Interactions
    • MAOIs: Risk of serotonin syndrome; avoid concurrent use

    • NSAIDs, anticoagulants: Increased risk of bleeding

    • Other SSRIs/SNRIs: Risk of serotonin syndrome

    • CYP enzyme inhibitors/inducers: May affect escitalopram levels

    • Alcohol: Escitalopram does not potentiate alcohol effects, but caution is still advised

    👶 Use in Pregnancy and Lactation
    • Pregnancy Category (varies by country): C

      • Potential risks include persistent pulmonary hypertension of the newborn (PPHN) and neonatal withdrawal syndrome

    • Breastfeeding: Present in breast milk; caution advised

    🧬 Genetic Considerations
    • Individuals with CYP2C19 poor metabolizer status may have increased drug levels and a higher risk of side effects.

    • Genetic testing can help guide dosing in some cases.

    📊 Comparative Notes

    Compared to other SSRIs:

    • More selective for serotonin reuptake inhibition

    • Generally better tolerated

    • Fewer drug-drug interactions

    • Commonly preferred in the elderly and those sensitive to side effects

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