If you have a stuffy nose, coughing, or itchy or watery eyes because of allergies or hay fever, Phenergan Elixir can help. No matter what time of year it is, Phenergan can help right away.
Nausea and Motion Sickness AidThis product is great for people who need reliable relief when travelling or having stomach problems because it is made to help with nausea, vomiting, and motion sickness.
Escitalopram, tablets are used to relieve the symptoms of depression, anxiety, and obsessive-compulsive disorder (OCD) in adults. This medication works by increasing the levels of serotonin, a natural substance in the brain that helps maintain mental balance.
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How does Mounjaro work?
Mounjaro can also improve the way your body breaks down sugars and fats, leading to weight loss in some patients.
How long does it take for Mounjaro to work?
Very common side effects of Mounjaro include:
Are there any long-term side effects?
Are there any serious side effects of Mounjaro?
How to take Mounjaro for type 2 diabetes
Interactions with other medications
Interactions with food/drinks
Will tripeptide become available for weight loss in the UK?
What medication can I take to help me lose weight?
Mounjaro weight loss injections
Available off-label if prescribed for weight loss:
Weight loss tablets
Weight Loss Treatments
Use this flavoured laxative to return your bowel movements to normal health.
Laxido orange
Laxido paediatric
Laxido SachetsLaxido Sachets orange powder is an orange-flavored laxative for use in the treatment of constipation and is especially effective if you have been constipated for a long time. It may also be used to clear fecal impaction, which may occur if you have been constipated for a long time. The active ingredient is Macrogol which is an osmotic laxative, this makes the feces softer and easier to pass, giving you gentle relief. The electrolytes help to maintain the body’s normal sodium, potassium, and water levels whilst treating constipation.
How do I take Laxido Sachets Orange Powder?Empty the Laxido sachet of powder into a glass of water, stir, and drink.
For constipation, the usual dose is one sachet taken one to three times daily. A course of treatment should last no longer than 2 weeks unless you have other conditions or are taking medication that causes constipation.
For fecal impaction, the usual dose is eight sachets daily. All eight sachets must be taken within six hours. If you have a heart condition, do not take more than two sachets (in 250ml of water) in any one hour. A course of treatment should last no longer than three days.
Laxido Sachets contains the active ingredient Macrogol 3350, which is a laxative used for the treatment of constipation, especially if you have been constipated for a long time. It is also used to treat a build-up of hard feces in your bowel which may be a result of long-term constipation (this is known as fecal impaction).
Macrogol 3350 makes your feces softer and easier to pass, giving you relief from constipation. The electrolytes help to maintain your body’s normal levels of sodium, potassium, and water while you are being treated for constipation.
Escitalopram, tablets are used to relieve the symptoms of depression, anxiety, and obsessive-compulsive disorder (OCD) in adults. This medication works by increasing the levels of serotonin, a natural substance in the brain that helps maintain mental balance.
Escitalopram is a widely prescribed antidepressant medication that belongs to a class of drugs known as Selective Serotonin Reuptake Inhibitors (SSRIs). It is primarily used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Below is a comprehensive overview of the drug:
🔬 Chemical and Pharmacological DetailsGeneric Name: Escitalopram
Brand Names: Lexapro (USA), Cipralex (EU), among others
Chemical Structure: (S)-(+)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
Molecular Formula: C20H21FN2O
Drug Class: SSRI (Selective Serotonin Reuptake Inhibitor)
Escitalopram is the S-enantiomer of citalopram, meaning it is the more pharmacologically active part of the citalopram molecule.
🧠 Mechanism of ActionEscitalopram works by increasing serotonin levels in the brain. It does this by inhibiting the reuptake (reabsorption) of serotonin (5-HT) into the presynaptic neuron, thereby increasing its availability in the synaptic cleft. This improved serotonin signaling is believed to enhance mood and reduce anxiety.
💊 Therapeutic UsesMajor Depressive Disorder (MDD)
Generalized Anxiety Disorder (GAD)
Obsessive-Compulsive Disorder (OCD) – off-label
Panic Disorder – off-label
Social Anxiety Disorder (SAD) – off-label
Post-Traumatic Stress Disorder (PTSD) – off-label
Premenstrual Dysphoric Disorder (PMDD) – off-label
Typical Adult Dose for Depression or Anxiety:
Initial: 10 mg once daily
Maximum: 20 mg/day
Elderly or Hepatic Impairment:
Recommended: Start at 5 mg daily
Pediatric Use:
Approved for adolescents (≥12 years) in some countries
It is usually taken orally once daily, with or without food.
⏳ PharmacokineticsBioavailability: ~80%
Time to peak plasma concentration: 4–5 hours
Half-life: ~27–32 hours
Metabolism: Primarily in the liver via CYP2C19, CYP2D6, and CYP3A4
Excretion: Renal (kidneys)
Black Box Warning (USA): May increase the risk of suicidal thoughts and behaviors in children, adolescents, and young adults.
Serotonin Syndrome: Risk increases when combined with other serotonergic agents (e.g., MAOIs, triptans, tramadol).
QT Prolongation: Can cause abnormal heart rhythms at higher doses.
Discontinuation Syndrome: Abrupt stopping may lead to symptoms like dizziness, insomnia, irritability, and brain “zaps”.
Nausea
Headache
Drowsiness or insomnia
Dry mouth
Increased sweating
Sexual dysfunction (e.g., decreased libido, delayed ejaculation)
Fatigue or dizziness
Appetite or weight changes
Concurrent use with monoamine oxidase inhibitors (MAOIs)
Known hypersensitivity to escitalopram or citalopram
Use with pimozide (due to QT prolongation risk)
MAOIs: Risk of serotonin syndrome; avoid concurrent use
NSAIDs, anticoagulants: Increased risk of bleeding
Other SSRIs/SNRIs: Risk of serotonin syndrome
CYP enzyme inhibitors/inducers: May affect escitalopram levels
Alcohol: Escitalopram does not potentiate alcohol effects, but caution is still advised
Pregnancy Category (varies by country): C
Potential risks include persistent pulmonary hypertension of the newborn (PPHN) and neonatal withdrawal syndrome
Breastfeeding: Present in breast milk; caution advised
Individuals with CYP2C19 poor metabolizer status may have increased drug levels and a higher risk of side effects.
Genetic testing can help guide dosing in some cases.
Compared to other SSRIs:
More selective for serotonin reuptake inhibition
Generally better tolerated
Fewer drug-drug interactions
Commonly preferred in the elderly and those sensitive to side effects